Table 3.
Adverse events related to either chemotherapy in the triple-negative cohort (cohort 1) (n, %)
| Toxicity | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|
| Neutrophil count decreased | 2(10) | 9(45) | 4(20) |
| White blood cell decreased | 2(10) | 3(15) | -- |
| Fatigue | 10(50) | 1(5) | -- |
| Peripheral sensory neuropathy | 7(35) | -- | -- |
| Anemia | 3(15) | 3(15) | -- |
| Alopecia | 5(25) | -- | -- |
| Diarrhea | 2(10) | 2(10) | -- |
| Infusion related reaction | 4(20) | -- | -- |
| Nausea | 4(20) | -- | -- |
| Dysgeusia | 3(15) | -- | -- |
| Hyponatremia | 2(10) | 1(5) | -- |
| Mucositis oral | 3(15) | -- | -- |
| Constipation | 2(10) | -- | -- |
| Creatinine increased | 2(10) | -- | -- |
| Generalized muscle weakness | 1(5) | 1(5) | -- |
| Platelet count decreased | 2(10) | -- | -- |
| Rash acneiform | 1(5) | 1(5) | -- |
| Urinary tract infection | 2(10) | -- | -- |
| Alanine aminotransferase increased | 1(5) | -- | -- |
| Anorexia | 1(5) | -- | -- |
| Arthralgia | 1(5) | -- | -- |
| Aspartate aminotransferase increased | 1(5) | -- | -- |
| Blood bilirubin increased | 1(5) | -- | -- |
| Blurred vision | 1(5) | -- | -- |
| Chills | 1(5) | -- | -- |
| Dehydration | 1(5) | -- | -- |
| Dry mouth | 1(5) | -- | -- |
| Dyspepsia | 1(5) | -- | -- |
| Dyspnea | -- | 1(5) | -- |
| Enterocolitis infectious | -- | 1(5) | -- |
| Fall | 1(5) | -- | -- |
| Febrile neutropenia | -- | 1(5) | -- |
| Gastroesophageal reflux disease | 1(5) | -- | -- |
| Gastrointestinal disorders - Other, specify | 1(5) | -- | -- |
| Insomnia | 1(5) | -- | -- |
| Myalgia | 1(5) | -- | -- |
| Paresthesia | 1(5) | -- | -- |
| Pruritus | 1(5) | -- | -- |
| Rash maculo-papular | 1(5) | -- | -- |
| Skin infection | -- | 1(5) | -- |
| Vaginal dryness | 1(5) | -- | -- |
| Vomiting | 1(5) | -- | -- |
| Weight loss | 1(5) | -- | -- |