Table 2. Meta-analysis of the relationship between venous thromboembolism and the clinical characteristics of patients with multiple myeloma.
| Association | Studies | Total patients | Effect index | Heterogeneity test | |||||
|---|---|---|---|---|---|---|---|---|---|
| Quantity | Model | 95% CI | P | I2 (%) | P | ||||
| Age | 3 | 1,627 | RR | Random | 1.33 (0.40 to 4.44) | to0.64 | 97 | <0.01 | |
| Gender | 6 | 42,437 | RR | Random | 1.13 (0.76 to 1.69) | 0.54 | 94 | <0.01 | |
| Race | 3 | 10,659 | RR | Fixed | 0.89 (0.75 to 1.06) | 0.21 | 50 | 0.14 | |
| ECOG score | 3 | 6,561 | RR | Fixed | 1.01 (0.99 to 1.03) | 0.56 | 0 | 0.79 | |
| Globulin type | 2 | 6,267 | RR | Random | 1.06 (0.97 to 1.15) | 0.22 | 57 | 0.13 | |
| Light-chain type | 2 | 6,087 | RR | Random | 0.97 (0.81 to 1.16) | 0.72 | 65 | 0.09 | |
| β2 microglobulin | 3 | 4,893 | SMD | Fixed | –0.09(–0.18 to –0.01) | 0.02 | 0 | 0.81 | |
| Creatinine | 2 | 6,226 | SMD | Fixed | –0.03 (–0.10 to 0.04) | 0.35 | 0 | 0.61 | |
| Calcium | 2 | 6,215 | SMD | Fixed | –0.00 (–0.07 to 0.07) | 1.00 | 0 | 1.00 | |
| Platelet | 3 | 6,625 | SMD | Fixed | 0.01 (–0.06 to 0.08) | 0.84 | 0 | 0.52 | |
| Hemoglobin | 3 | 6,623 | SMD | Random | 0.04 (–0.18 to 0.26) | 0.73 | 84 | <0.01 | |
RR, relative risk; SMD, standard mean difference; ECOG, Eastern Cooperative Oncology Group.