Table 5. Univariate and multivariate analyses of PCa-associated factors in patients with PSA levels of 2.5–20.0 ng/mL.
Variables | Univariate | Multivariate | |||
---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | ||
Age (years) | |||||
<68.5 | – | – | – | – | |
≥68.5 | 3.20 (1.921–5.321) | <0.001 | 3.51 (1.920–6.417) | <0.001 | |
PSA (ng/mL) | |||||
<6.315 | – | – | – | – | |
≥6.315 | 3.43 (2.026–5.814) | <0.001 | – | 0.656 | |
TPV (mL) | |||||
≥34.50 | – | – | – | – | |
<34.50 | 3.62 (2.137–6.133) | <0.001 | – | – | |
PZV (mL) | |||||
≥19.85 | – | – | – | – | |
<19.85 | 2.31 (1.413–3.785) | 0.001 | – | – | |
PZ-PSAD (ng/mL2) | |||||
<0.368 | – | – | – | – | |
≥0.368 | 5.04 (2.991–8.475) | <0.001 | – | 0.370 | |
TZ-PSAD (ng/mL2) | |||||
<0.353 | – | – | – | – | |
≥0.353 | 5.47 (3.229–9.268) | <0.001 | 2.26 (1.019–4.993) | 0.045 | |
PSAD (ng/mL2) | |||||
<0.218 | – | – | – | – | |
≥0.218 | 8.16 (4.612–14.419) | <0.001 | 3.51 (1.306–9.415) | 0.013 |
PCa, prostate cancer; PSA, prostate-specific antigen; OR, odds ratio; CI, confidence interval; TPV, total prostate volume; PZV, peripheral zone volume; PZ-PSAD, peripheral zone prostate-specific antigen density; TZ-PSAD, transition zone prostate-specific antigen density.