Table 1. Baseline characteristics of patients with pulmonary metastases.
Characteristic | Primary cohort | Matching cohort | |||||
---|---|---|---|---|---|---|---|
Surgery | Chemotherapy | P value | Surgery | Chemotherapy | P value | ||
N | 43 | 79 | 43 | 43 | |||
Age, years [median] | 53 [41–58] | 54 [39–60] | 0.891† | 53 [41–58] | 51 [38–59] | 0.688† | |
Sex, female | 20 [47] | 44 [56] | 0.332 | 20 [47] | 22 [51] | 0.666 | |
DFI, months [median] | 24 [13–36] | 21 [7–44] | 0.459† | 24 [13–36] | 20 [6–27] | 0.083† | |
Smoking, yes | 11 [26] | 15 [19] | 0.396 | 11 [26] | 7 [13] | 0.289 | |
Pathology for primary lesion | 0.096 | 0.239 | |||||
Cancer | 31 [72] | 63 [80] | 31 [72] | 33 [77] | |||
Sarcoma | 12 [28] | 12 [15] | 12 [28] | 8 [19] | |||
Germ cell tumor | 0 | 4 [5] | 0 | 2 [4] | |||
Completely removed | 43 [100] | 54 [83] | 0.003‡* | 43 [100] | 43 [100] | ||
No. of metastases | <0.001* | <0.001* | |||||
Single | 36 [84] | 7 [9] | 36 [84] | 6 [14] | |||
2–3 | 6 [14] | 22 [28] | 6 [14] | 16 [37] | |||
>3 | 1 [2] | 50 [63] | 1 [2] | 21 [49] | |||
Adjuvant therapy | 0.240‡ | 0.848‡ | |||||
No | 24 [56] | 28 [35] | 24 [56] | 20 [46] | |||
Targeted therapy | 1 [2] | 6 [8] | 1 [2] | 1 [2] | |||
Radiotherapy | 3 [7] | 12 [15] | 3 [7] | 5 [12] | |||
Combination therapy | 8 [19] | 18 [23] | 8 [19] | 11 [26] | |||
Else | 7 [16] | 15 [19] | 7 [16] | 6 [14] | |||
Adjuvant or not | 0.030* | 0.388 | |||||
No | 24 [56] | 28 [35] | 24 [56] | 20 [46] | |||
Yes | 19 [44] | 51 [65] | 19 [44] | 23 [54] | |||
Diameter, mm§ [median] | 20 [14–30] | 45 [30–74] | <0.001†* | 20 [14–30] | 40 [27–78] | <0.001†* |
The median is followed by the interquartile range; data are expressed as n [%] unless otherwise specified. †, Mann-Whitney U test; ‡, Fisher’s exact test; §, sum of the diameter for metastatic lesions; *, P<0.05. N, number; DFI, disease-free interval.