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. 2023 Mar 31;12(3):406–424. doi: 10.21037/tau-23-21

Figure 2.

Figure 2

Construction of the mutation classifier and internal validation in the CheckMate ICI therapy cohort. (A) Cross-validation for tuning the parameter selection in the Lasso logistic regression. (B) Lasso logistic regression of the 41 mutated genes. (C) The distribution of the risk scores and OS status in the training set. (D) Kaplan-Meier curves show the difference in OS between the low- and high-risk groups in the training set. (E) The distribution of the risk scores and OS status in the validation set. (F) Kaplan-Meier curves show the difference in OS between the low- and high-risk groups in the validation set. ICI, immune checkpoint inhibitor; AUC, area under the receiver operating characteristic curve; Lasso, least absolute shrinkage and selection operator; OS, overall survival; HR, hazard ratio.