Table 2. Posttreatment Prognoses Across the 3 Therapy Groups and for Each Therapy Group.
| IGA score at baseline | Transition probability, mean (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|
| 0-1 mo | 1-12 mo | |||||||
| IGA 0/1 | IGA 2 | IGA 3 | IGA 4 | IGA 0/1 | IGA 2 | IGA 3 | IGA 4 | |
| Overall | ||||||||
| IGA 0/1 | 0.80 (0.78-0.82) | 0.12 (0.10-0.13) | 0.06 (0.05-0.08) | 0.02 (0.01-0.03) | 0.54 (0.51-0.57) | 0.26 (0.23-0.28) | 0.16 (0.14-0.17) | 0.05 (0.04-0.06) |
| IGA 2 | 0.18 (0.17-0.19) | 0.74 (0.73-0.75) | 0.06 (0.06-0.07) | 0.01 (0.01-0.02) | 0.34 (0.33-0.35) | 0.48 (0.47-0.50) | 0.14 (0.13-0.15) | 0.04 (0.03-0.04) |
| IGA 3 | 0.18 (0.17-0.19) | 0.13 (0.12-0.13) | 0.68 (0.66-0.68) | 0.02 (0.02-0.02) | 0.35 (0.34-0.36) | 0.24 (0.23-0.25) | 0.37 (0.36-0.38) | 0.04 (0.03-0.04) |
| IGA 4 | 0.19 (0.18-0.21) | 0.14 (0.13-0.15) | 0.07 (0.06-0.08) | 0.60 (0.58-0.61) | 0.36 (0.34-0.37) | 0.29 (0.28-0.31) | 0.14 (0.12-0.15) | 0.22 (0.20-0.23) |
| Traditional | ||||||||
| IGA 0/1 | 0.83 (0.80-0.85) | 0.10 (0.08-0.12) | 0.05 (0.04-0.07) | 0.02 (0.01-0.03) | 0.61 (0.57-0.65) | 0.19 (0.16-0.23) | 0.15 (0.12-0.18) | 0.05 (0.03-0.07) |
| IGA 2 | 0.15 (0.14-0.16) | 0.78 (0.76-0.80) | 0.05 (0.05-0.06) | 0.01 (0.01-0.02) | 0.31 (0.29-0.33) | 0.54 (0.52-0.56) | 0.12 (0.11-0.13) | 0.04 (0.03-0.04) |
| IGA 3 | 0.15 (0.13-0.16) | 0.10 (0.09-0.11) | 0.74 (0.72-0.75) | 0.02 (0.01-0.02) | 0.30 (0.29-0.32) | 0.20 (0.19-0.21) | 0.47 (0.45-0.48) | 0.03 (0.02-0.04) |
| IGA 4 | 0.17 (0.15-0.20) | 0.12 (0.10-0.14) | 0.03 (0.02-0.04) | 0.67 (0.64-0.70) | 0.33 (0.30-0.37) | 0.23 (0.20-0.26) | 0.12 (0.10-0.14) | 0.31 (0.28-0.34) |
| Systemic | ||||||||
| IGA 0/1 | 0.85 (0.81-0.89) | 0.05 (0.03-0.07) | 0.07 (0.04-0.09) | 0.04 (0.01-0.06) | 0.61 (0.56-0.66) | 0.18 (0.14-0.22) | 0.16 (0.12-0.20) | 0.05 (0.03-0.07) |
| IGA 2 | 0.25 (0.23-0.27) | 0.70 (0.68-0.72) | 0.04 (0.03-0.05) | 0.01 (0.00-0.01) | 0.38 (0.36-0.41) | 0.47 (0.45-0.49) | 0.12 (0.11-0.14) | 0.03 (0.02-0.03) |
| IGA 3 | 0.17 (0.15-0.18) | 0.12 (0.11-0.13) | 0.70 (0.68-0.71) | 0.02 (0.01-0.02) | 0.33 (0.31-0.34) | 0.24 (0.23-0.26) | 0.40 (0.38-0.42) | 0.03 (0.03-0.04) |
| IGA 4 | 0.16 (0.14-0.19) | 0.10 (0.08-0.12) | 0.06 (0.04-0.07) | 0.68 (0.65-0.71) | 0.30 (0.28-0.33) | 0.27 (0.24-0.29) | 0.14 (0.12-0.16) | 0.29 (0.26-0.32) |
| Biologic | ||||||||
| IGA 0/1 | 0.73 (0.69-0.77) | 0.20 (0.16-0.23) | 0.08 (0.05-0.10) | 0 | 0.41 (0.36-0.45) | 0.39 (0.35-0.43) | 0.16 (0.13-0.19) | 0.04 (0.02-0.06) |
| IGA 2 | 0.15 (0.13-0.17) | 0.73 (0.71-0.75) | 0.10 (0.08-0.11) | 0.02 (0.01-0.03) | 0.34 (0.32-0.36) | 0.43 (0.41-0.45) | 0.18 (0.17-0.20) | 0.05 (0.04-0.06) |
| IGA 3 | 0.23 (0.21-0.24) | 0.16 (0.15-0.17) | 0.59 (0.57-0.60) | 0.03 (0.02-0.03) | 0.42 (0.40-0.44) | 0.29 (0.27-0.30) | 0.25 (0.24-0.27) | 0.04 (0.04-0.05) |
| IGA 4 | 0.23 (0.21-0.25) | 0.18 (0.17-0.20) | 0.10 (0.08-0.11) | 0.49 (0.47-0.51) | 0.41 (0.39-0.44) | 0.34 (0.32-0.37) | 0.14 (0.13-0.16) | 0.10 (0.09-0.12) |
Abbreviation: IGA, Investigator’s Global Assessment.