Table 3. Comparison of Posttreatment Prognoses for Biologic Therapy vs Traditional and Systemic Therapies.

IGA score at baseline	Difference in transition probability, mean (95% CI)
	0-1 mo				1-12 mo
	IGA 0/1	IGA 2	IGA 3	IGA 4	IGA 0/1	IGA 2	IGA 3	IGA 4
Biologic vs traditional therapy
IGA 0/1	−0.10 (−0.14 to −0.05)	0.10 (0.06 to 0.14)	0.02 (−0.01 to 0.05)	−0.02 (−0.03 to −0.01)	−0.20 (−0.26 to −0.14)	0.20 (0.14 to 0.25)	0.01 (−0.03 to 0.05)	−0.01 (−0.03 to 0.02)
IGA 2	0.00 (−0.02 to 0.02)	−0.05 (−0.07 to −0.02)	0.04 (0.03 to 0.06)	0.01 (0.00 to 0.01)	0.03 (0.00 to 0.06)	−0.11 (−0.14 to −0.08)	0.07 (0.04 to 0.09)	0.02 (0.00 to 0.03)
IGA 3	0.08 (0.06 to 0.10)	0.06 (0.04 to 0.08)	−0.15 (−0.17 to −0.13)	0.01 (0.00 to 0.01)	0.12 (0.09 to 0.14)	0.09 (0.06 to 0.11)	−0.22 (−0.24 to −0.19)	0.01 (0.00 to 0.02)
IGA 4	0.06 (0.02 to 0.09)	0.06 (0.03 to 0.09)	0.06 (0.05 to 0.08)	−0.18 (−0.22 to −0.14)	0.08 (0.04 to 0.12)	0.11 (0.07 to 0.15)	0.02 (0.00 to 0.05)	−0.21 (−0.25 to −0.18)
Biologic vs systemic therapy
IGA 0/1	−0.12 (−0.17 to −0.07)	0.15 (0.11 to 0.19)	0.01 (−0.03 to 0.04)	−0.04 (−0.06 to −0.01)	−0.20 (−0.27 to −0.14)	0.21 (0.16 to 0.27)	0.00 (−0.05 to 0.05)	−0.01 (−0.04 to 0.02)
IGA 2	−0.10 (−0.12 to −0.07)	0.03 (0.01 to 0.06)	0.05 (0.04 to 0.07)	0.01 (0.00 to 0.02)	−0.05 (−0.08 to −0.02)	−0.04 (−0.07 to −0.01)	0.06 (0.04 to 0.09)	0.03 (0.01 to 0.04)
IGA 3	0.06 (0.04 to 0.08)	0.04 (0.02 to 0.06)	−0.11 (−0.14 to −0.09)	0.01 (0.00 to 0.02)	0.09 (0.07 to 0.12)	0.04 (0.02 to 0.07)	−0.15 (−0.17 to −0.12)	0.01 (0.00 to 0.02)
IGA 4	0.06 (0.03 to 0.09)	0.08 (0.06 to 0.11)	0.04 (0.02 to 0.06)	−0.19 (−0.23 to −0.15)	0.11 (0.07 to 0.14)	0.08 (0.04 to 0.11)	0.01 (−0.02 to 0.03)	−0.19 (−0.23 to −0.16)

Abbreviation: IGA, Investigator’s Global Assessment.