Table 2.
Study | Country | No. of subjects | Age | Analysis methods | Findings in obese cohorts |
---|---|---|---|---|---|
Gao et al. [35] 2018 | China | NW (25), OW (22), OB (145) | Adults | 16S rRNA sequencing | ↓ Rikenellaceae and Christensenellaceae |
↓ Bifidobacterium, Oscillospira and Akkermansia | |||||
Zhou et al. [36] 2022 | US and UK | NW (6,573), OW (2,802), OB (1,159) | Adults | 16S rRNA sequencing | ↓Akkermansia muciniphila |
Ignacio et al. [8] 2016 | Brazil | NW (30), OW (24), OB (30) | 6–10 Years old | Culture and real-time PCR | ↑Bacteroides |
Kalliom ki et al. [37] 2008 | Spain | NW (24), OB (25) | 7 Years old | FISH and real-time PCR | ↓ Bifidobacterium |
Crovesy et al. [38] 2017 | Systematic review | 14 Articles | Adults | Real-time PCR | ↓Lactobacillus paracasei |
16S rRNA sequencing | ↑Lactobacillus reuteri and Lactobacillus gasseri |
NW, normal weight; OW, overweight; OB, obesity; FISH, fluorescent in situ hybridization with microscopic and flow cytometry detection; PCR, polymerase chain reaction.