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. Author manuscript; available in PMC: 2023 Apr 7.
Published in final edited form as: Leuk Lymphoma. 2021 Jun 28;62(8):1940–1948. doi: 10.1080/10428194.2021.1885664

Table 2:

Associations with adverse outcomes

Predictor Death Death/Intubation/High Flow nasal cannula
OR (95%CI) P-value OR (95%CI) P-value
Gender: Male vs. female 2.3 (0.55,9.61) 0.33 1.44 (0.48,4.32) 0.59
BMI: > 30 vs < 30 2.0 (0.5,8) 0.44 1.66 (0.5,5.49) 0.53
History of current/former smoking: Yes vs. No 2.6 (0.7,9.8) 0.18 3.9 (1.27,11.98) 0.022
Age: >60 vs. < 60 years 4.5 (0.89,22.79) 0.09 4.46 (1.28,15.52) 0.027
≥ 3 comorbidities: Yes vs. No 6.55 (1.29,33.26) 0.019 3.37 (1.08,10.48) 0.055
Disease: AML vs. all others 4.7 (1.2,18.3) 0.028 2.99 (0.93,9.6) 0.072
Treatment prior to COVID-19:
  – Last treatment < 3 months vs. > 3 months
  – Prior allo-SCT vs. no prior allo-SCT

5.22 (1.03,26.45)
2.0 (0.5,8)

0.047
0.44

1.37 (0.47,4.04)
2.4 (0.73,7.83)

0.60
0.21
Laboratory values:
  – Neutropenia: ANC < 1000/uL vs. > 1000/uL
  – Lymphocytopenia: ALC < 500/uL vs. > 500/uL
  – Albumin: Alb < 3.5 vs. > 3.5
  – Creatinine 1.3: Yes vs. No
  – ALT > 55: Yes vs. No
  – AST > 37: Yes vs. No
  – Total bilirubin > 1.2: Yes vs. No

11.75 (2.72,50.74) 0.55 (0.14,2.22)
9.0 (1.92,42.14)
0.72 (0.13,3.94)
4.43 (0.88,22.17)
9.0 (1.92,42.14)
4.0 (0.68,23.67)

0.001*
0.48
0.004
1.0
0.079
0.004
0.13

4.85 (1.39,16.94)
0.24 (0.1–1.1)
8.8 (2.2,35.15))
1.1 (0.27,4.45)
3.61 (0.74,17.64)
5.48 (1.46,20.48)
1.86 (0.33,10.45)

0.018
0.081
0.003*
1.0
0.13
0.012
0.66
*

remains statistically significant after Bonferroni correction (p < 0.0033)