. 2023 Apr 6;149(6):512–520. doi: 10.1001/jamaoto.2023.0161

Table 2. Coprimary Effectiveness End Point Responses at Month 4 and Months 12 and 15.

End point	No./total No. (%)			Standardized mean difference, Treatment-control (95% CI)
End point	Treatment	Control	Treatment-control, RR (95% CI)	Standardized mean difference, Treatment-control (95% CI)
M4 AHI RR	46/88 (52.3)	9/46 (19.6)	32.7 (15.2 to 49.0)	0.725 (0.360 to 1.163)
M4 ODI RR	55/85 (62.5)	19/46 (41.3)	21.2 (3.3 to 38.1)	0.434 (0.070 to 0.843)
End point	Pooled 11-mo active therapy: treatment and control		Pooled therapy–performance goal of 50% (95% CI)	Standardized mean difference, pooled therapy–performance goal of 50% (95% CI)
M12/15 AHI RR	59/138 (42.5)		−7.5 (−16.0 to 1.4)	−0.151 (−0.330 to 0.015)
M12/15 ODI RR	83/138 (60.4)		10.4 (1.6 to 18.8)	0.214 (0.045 to 0.402)

Abbreviations: AHI, apnea-hypopnea index; M4, month 4; M12/15, month 12/15; ODI, oxygen desaturation index; RR, response rate.