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Therapeutic strategies to trigger endogenous neurogenesis. (A) Transplantation of biomaterials that mimic the mechanical properties of the spinal cord. (B) Transplantation of functional biomaterials loaded with neurotrophic factors. (C) Transplanting functional biomaterials for sustained small molecule drugs release. (D) Transplantation of exogenous stem cells. (E) Physiotherapy. MSC, mesenchymal stem cell; NSC, neural stem cell.
