Table 1.
Cohort characteristics for VDAART pregnant mothers and children at age 6 years with PFAS and metabolomic profiling.
| VDAART Cohort Characteristics and PFAS Exposures | ||
|---|---|---|
| Cohort Characteristics | ||
| Mothers | Children | |
| Number of subjects | 459 | 401 |
| BMI kg/m2, Mean (SD)1 | 28.8 (8.0) | 16.9 (2.9) |
| Age at collection, Mean (SD) | 27.4 (5.5) | 6.0 (0.1) |
| Gender, n (%) | ||
| Female | 459 (100.0) | 185 (46.1) |
| Male | - | 216 (53.9) |
| Race, n (%) | ||
| Black | 204 (44.4) | 197 (49.1) |
| White | 176 (38.3) | 129 (32.2) |
| Other | 79 (17.2) | 75 (18.7) |
| Ethnicity, n (%) | ||
| Hispanic or Latino | 128 (27.9) | 136 (33.9) |
| Not Hispanic or Latino | 331 (72.1) | 265 (66.1) |
| Study site, n (%) | ||
| Boston | 128 (27.9) | 114 (28.4) |
| San Diego | 157 (34.2) | 138 (34.4) |
| St. Louis | 174 (37.9) | 149 (37.2) |
| Household Income Category, n (%)2 | ||
| Low | 194 (56.1) | 172 (57.0) |
| Medium | 106 (30.6) | 87 (28.8) |
| High | 46 (13.3) | 43 (14.2) |
| Maternal Education Category, n (%)3 | ||
| Low | 287 (62.5) | 248 (61.8) |
| Medium | 110 (24.0) | 102 (25.4) |
| High | 62 (13.5) | 51 (12.7) |
| Vitamin D supplementation in pregnancy, n (%)4 | 227 (49.5) | 198 (49.4) |
| Vitamin D Level at Time of Collection (ng/mL), Mean (SD) | 32.4 (13.9) | 28.3 (9.7) |
1
BMI in mothers was reported as pre-pregnancy BMI
2
Income was categorized based on reported household yearly income in USD: Low (<$50,000/year), Medium ($50,000–$100,000/year), or High (>$100,000/year)
3
Maternal educational status was categorized based on maximum education level reported: Low (primary school, secondary school, or some college/junior college), Medium (technical/trade school or bachelor’s degree), or High (graduate degree)
4
Percent of mothers in the vitamin D supplementation group is shown; for children, the percent of children with mothers that received vitamin D supplementation in pregnancy is shown