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Drug-likeness properties of 7a-e along with MLN-4760 as a reference by the SwissADME server.
| Compound | Lipinski | Ghose | Veber | Egan | Muegge | Bioavailability Score | Lipinski's Violation |
|---|---|---|---|---|---|---|---|
| 7a | Yes | Yes | Yes | Yes | Yes | 0.55 | 0 |
| 7b | Yes | Yes | Yes | Yes | Yes | 0.55 | 0 |
| 7c | Yes | Yes | Yes | Yes | Yes | 0.55 | 0 |
| 7d | Yes | Yes | Yes | Yes | No | 0.55 | 0 |
| 7e | Yes | Yes | Yes | Yes | Yes | 0.55 | 0 |
| MLN-4760 (reference) | Yes | Yes | Yes | Yes | Yes | 0.55 | 0 |
