Table 1.

Summary of articles included in this review (n = 31)

Article [Refs.] (Author, Year, Journal)	Cancer types (No. patients)	Research question	Patient data sources, years	Cancer care continuum	Reporting quality
Abbas et al., 2021, Ann Surg Oncol [26]	Colon (n = 26,287) Lung (n = 16,645) Pancreatic (n = 6,183) Rectal (n = 3,174) Esophageal (n = 1,427)	Are county-level SVI and race/ethnicity associated with patterns of hospice utilization among those who underwent a cancer resection and who lived ≥ 30 days after the surgery?	Medicare, 2013–17	End-of-life	Excellent
Azap et al., 2020, Surgery [27]	Pancreatic (n = 18,841) Liver (n = 13,301)	Is county-level SVI associated with the probability of post-op textbook outcomes in those who underwent a cancer resection?	Medicare, 2013–17	Treatment Recovery	Excellent
Azap et al., 2021, Ann Surg Oncol [28]	Pancreatic (n = 15,931)	Are county-level SVI and race/ethnicity associated with the probability of undergoing a cancer resection or receiving chemotherapy?	SEER-Medicare, 2004–16	Treatment	Excellent
Azap et al., 2021, JAMA Surg [29]	Liver (n = 10,888)	Are county-level SVI and race/ethnicity associated with the probability of undergoing a cancer resection or transplant?	SEER-Medicare, 2004–17	Treatment	Excellent
Barmash et al., 2020, J Am Coll Surg [30]	Colon (n ~ 35,324)	Is county-level SVI associated with emergent vs. non-emergent colon resection and post-op outcomes?	Medicare, 2016–17	Treatment Treatment Recovery	Low
Bhandari et al., 2021, Blood [31]	Acute myeloid leukemia (n = 652 in California)	Is census tract-level SVI associated with 1-year non-relapse mortality?	Single institution(s) in California, 2013–19	N/A	Low
Bowers et al., 2020, Lab Invest [32]	Leukemia (NR; 727 counties in 14 states)	Does leukemia subtype incidence vary within and between areas of SES disparity? SDOH Measures: Gini, income inequality, county-level SVI, residential segregation, rurality	SEER-21, 2000–16	Diagnosis	Low
Carmichael et al., 2022, Am J Surg [33]	Colorectal (n = 392)	Is census tract-level SVI associated with increased risk of post-op 30-day morbidity following colectomy?	Single institutions in Colorado, 2013–2017	Treatment Recovery	Good
Dalmacy et al., 2021, Surgery [34]	Pancreatic (NR) Liver (NR)	Is county-level SVI associated with risk of fragmented post-op care among those who had ≥ 1 readmission within 90 days?	Medicare, 2013–17	Treatment Treatment Recovery	Excellent
Diaz et al., 2021, Ann Surg Oncol [35]	Lung (n = 14,403 in California) Rectal (n = 7,520 in CA) Pancreatic (n = 3,744 in CA) Esophageal (n = 1,270 in CA)	Is county-level SVI associated with utilization of high-volume hospitals for high-risk cancer operations?	California OSHPD, 2012–16	Treatment	Excellent
Diaz et al., 2021, J Gastrointest Surg [36]	Colon (n = 33,312)	Is county-level SVI associated with the probability of having a non-elective vs. elective colon resection?	MedPAR, 2016–17	Treatment Treatment Recovery	Excellent
Diaz et al., 2021, J Surg Oncol [37]	Lung (n = 33,803) Colon (n = 21,939)	What is the impact of county-level SVI and racial/ethnic residential diversity on post-op outcomes among those who underwent a cancer resection?	Medicare, 2016–17	Treatment Treatment Recovery	Excellent
Diaz et al., 2021, Surgery [38]	Pancreatic (n = 13,393) Liver (n = 3,594)	Is county-level SVI associated with use of a high-volume or Magnet recognition hospital?	Medicare, 2013–17	Treatment Treatment Recovery	Excellent
Ganatra et al., 2021, Circulation [39]	Any (NR)	Is county-level SVI associated with mortality from cardiovascular disease and concomitant cancer (cardio-oncology)?	CDC WONDER, 2014–18	N/A	Low
Grant et al., 2021, Blood [40]	Liquid tumors (e.g., multiple myeloma, leukemia, lymphoma) (n = 338 in North Carolina)	Is county-level SVI associated with physical frailty?	Carolina Senior Registry, NR Registry for Adults with PCDs, NR	N/A	Low
Grant et al., 2021, J Clin Oncol [41]	Multiple myeloma (NR; 456 trials registered in North Carolina)	Is county-level SVI associated with multiple myeloma trial availability in North Carolina?	ClinicalTrials.gov, accessed 01/24/2021	Treatment	Low
Hawley et al., 2022 JAMA Netw Open [42]	Any, except NMSCs (n = 4,749)	Is there a spatiotemporal association in COVID-19 outcomes?	CCC19, Mar.–Nov. 2020	Treatment	Excellent
Hyer et al., 2021, J Am Coll Surg [43]	Colon (n = 113,929) Lung (n = 70,642) Rectal (n = 14,849) Esophageal (n = 4,380)	Are there differences in textbook outcomes relative to county-level SVI and race/ethnicity among those who underwent a cancer operation?	Medicare, 2013–17	Treatment Treatment Recovery	Excellent
Labiner et al., 2022, J Gastrointest Surg [44]	Pancreas? Liver? (n = 26,540)	Does county-level SVI subtheme analysis in patients undergoing hepatopancreatic surgery better stratify potential gaps in identifying risks of post-op complications?	Medicare, 2013–17	Treatment Recovery	Good
McAlarnen et al., 2021, Gynecol Oncol [45]	Ovarian, uterine, cervical, or vaginal/vulvar (n = 270 in NYC)	Is census tract-level SVI associated with the utilization of virtual gynecologic oncology visits at the beginning of the COVID-19 pandemic?	Single institution(s) in NYC, 2020	Survivorship Care	Good
McAlarnen et al., 2022, Cancer Epidemiol Biomark Prev [46]	Cervical (n = 66 in Milwaukee, Wisconsin)	Are demographic and geographic factors (e.g., census tract-level SVI) associated with diagnosis of locally advanced cervical cancer?	Single institution(s) in Milwaukee, Wisconsin, 2016–21	Diagnosis	Low
Mock et al., 2021, Transplant Cell Ther [47]	Acute myeloid leukemia (n = 818 in Virginia)	Do hematopoietic cell transplantation rates for acute myeloid leukemia vary between different regions in Virginia? Or vary by census tract-level SVI?	Virginia Cancer Registry, 2013–17	Treatment	Excellent
Pan et al., 2021, Hepatology [48]	Liver (n = 99 in NYC)	Do neighborhood-level (e.g., census tract-level) characteristics impact alcohol-associated liver disease outcomes (including development of HCC)?	Single institution(s) in NYC, 2012–19	Prevention Diagnosis	Low
Papageorge et al., 2021, J Am Coll Surg [49]	Liver (n = 19,751 in 12 states)	Was county-level SVI associated with the impact of Medicaid expansion on the diagnosis of HCC?	SEER, 2010–16	Diagnosis	Excellent
Parks et al., 2022, JAMA [50]	Any (n = 3,619,393 in 1,206 counties)	Is county-level tropical cyclone exposure associated with county-level cause-specific mortality (including cancer-specific mortality)?	CDC NCHS, 1988–18	Prevention	Excellent
Puvvula et al., 2021, Water [51]	All pediatric cancers (n = 2,559 in Nebraska)	Are atrazine concentrations at watersheds associated with the incidence of pediatric cancers in Nebraska? Model: adjusted for census tract-level SVI	Nebraska Cancer Registry, 1987–16	Prevention Diagnosis	Good
Rice et al., 2021, Ann Surg Oncol [52]	Liver (n = 14,369)	What factors (e.g., county-level SVI) are associated with hospice utilization and end-of-life healthcare expenditures among those who died of HCC?	SEER-Medicare, 2004–16	End-of-life	Excellent
Taylor et al., 2021, Gastroenterology [53]	Colon (n = 146,041)	Is Medicaid-Medicare dual eligibility status associated with non-elective surgery for colon cancer and variation in outcomes and spending? Analyses: stratified by county-level SVI	Medicare, 2014–18	Treatment	Low
Ying et al., 2020, Hepatology [54]	Liver (n = 143 in NYC)	Are racial and neighborhood-level factors (e.g., SVI) associated with adverse outcomes in those with cirrhosis due to viral hepatitis?	Single institutions(s) in NYC, 2012–19	Prevention Diagnosis	Low
Ying et al., 2021, Hepatology [55]	Liver (n = 98 in NYC)	Is SVI associated with advanced-stage HCC diagnosis in those with cirrhosis due to viral hepatitis?	Single institution(s) in NYC, 2012–20	Prevention Diagnosis	Low
Zhang et al., 2022, Health Aff (Project Hope) [56]	Colon (n = 203,732)	Is county-level SVI associated with unplanned surgeries for one of three specified access-sensitive conditions (including colectomy for colon cancer)?	MedPAR, 2014–18	Treatment	Excellent

^*Nationwide, unless otherwise indicated

SVI social vulnerability index, post-op post-operative, SEER Surveillance, Epidemiology, and End Results Program, SDOH social determinants of health, SES socioeconomic status, CA California, OSHPD Office of State-wide Health Planning and Development, MedPAR Medicare Provider Analysis and Review, CDC Centers for Disease Control and Prevention, WONDER Wide-ranging Online Data for Epidemiologic Research, PCD plasma cell disorder, NMSC non-melanoma skin cancer, COVID-19 coronavirus disease 2019, CCC19 COVID-19 and Cancer Consortium, NYC New York City, HCC hepatocellular carcinoma, NCHS National Center for Health Statistics, NR not reported