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. 2023 Mar 24;11:1038937. doi: 10.3389/fped.2023.1038937

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© 2023 Walker, Aquilina, Spoudeas, Pilotto, Gan and Meijer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Patient selection criteria for observation vs. treatment in SIOP LGG 2 (004 randomised trial (17). (B) Comparison of LogMAR visual acuity results from SIOP LGG 2004 workshop comparing pre- and post- bilateral visual acuity for observation (top green graphs) and treatment (lower orange graphs) with vincristine and carboplatin in patients with NF1 (46).