Figure 6.
Change in the steady-state map boundaries in the case of continuously feeding a population of pure β crystals (left) and α crystals (right). The highest suspension density fed has an μ3,αin = 0.018 for the α-polymorph and an μ3,β = 0.49 for the β-polymorph, respectively. The other μ3,βin values are 25%, 50%, and 75% of the above reference value. Note that since a polymorphic pure suspension is fed to the MSMPR, only two steady-states are possible, i.e., the mixed steady-state (“mixed”, colored in a transparent green) and the pure steady-state of the polymorph being fed (β or α). The boundaries of the original steady-state map are shown with gray dashed lines for comparison. The green lines denote the 99% purity of the corresponding polymorph.