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. 2023 Mar 24;145(13):7361–7375. doi: 10.1021/jacs.2c13732

Table 2. IC50 Values for 1 and 14 against A549, U-87 MG, HeLa, and HEK-293 Cells under Different Conditions with Light Irradiation (λ > 610 nm, 23 mW cm–2, 28 J cm–2).

  IC50 (μM)
  MMP-2-positive
MMP-2-negative
conditions A549 U-87 MG HeLa HEK-293
1 0.78 ± 0.04 0.91 ± 0.03 3.06 ± 0.02 >4
1 + CA-074 Me 2.39 ± 0.02 2.72 ± 0.01 >4 >4
1 + SB-3CT 2.07 ± 0.01 2.55 ± 0.04 >4 >4
1 + SB-3CT + CA-074 Me >4 >4 >4 >4
14 >4 >4 >4 >4