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. 2023 Apr 6;23:323. doi: 10.1186/s12885-023-10792-8

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — The prognostic value of hub genes in patients with colorectal cancer (CRC). A-H The mRNA expression of the hub DEGs in different CRC stages was from the TCGA database with the web tool UALCAN. Data were normally distributed and one-way ANOVA with post hoc intergroup comparison by Tukey's test was used. ***, P < 0.001. A P value < 0.05 was considered significant. I-P Relationships of hub DEG expression with overall survival in patients with CRC in the cohort of GEO databases are shown. Log-rank test. A P < 0.05 was considered significant