Table 1.
Baseline characteristics of syphilis-seropositive pregnant women with treatment or treatment failure during pregnancy in Guangzhou, China, 2014–2016 (N = 1248)
| Variable | Women with untreated or inadequately treated N(%) |
Women with adequately treated N(%) |
Total N(%) |
P-valuea |
|---|---|---|---|---|
| Number | 379 (30.4) | 869 (69.6) | 1248 | |
| Age in years, mean ± SD | 30.2 ± 6.4 | 30.4 ± 5.7 | 30.3 ± 6.0 | 0.488b |
| Residence | < 0.001 | |||
| Local | 68 (18.5) | 300 (81.5) | 368 (29.5) | |
| Migrant | 311 (35.3) | 569 (64.7) | 880 (70.5) | |
| Marital status | < 0.001 | |||
| First marriage | 263 (26.5) | 729 (73.5) | 992 (79.5) | |
| Unmarried | 71 (50.0) | 71 (50.0) | 142 (11.4) | |
| Others | 45 (39.5) | 69 (60.5) | 114 (9.1) | |
| Education | < 0.001 | |||
| Middle school or less | 239 (35.1) | 442 (64.9) | 681 (54.6) | |
| High school and higher | 100 (21.7) | 362 (78.4) | 462 (37.0) | |
| Unknown | 40 (38.1) | 65 (61.9) | 105 (8.4) | |
| Occupation | < 0.001 | |||
| Officer / Business / Service industry | 25 (15.3) | 138 (84.7) | 163 (13.1) | |
| Farmer | 41 (26.3) | 115 (73.7) | 156 (12.5) | |
| Unemployed or Others or Unknown | 313 (33.7) | 616 (66.3) | 929 (74.4) | |
| Multipara | < 0.001 | |||
| No | 78 (17.9) | 359 (82.2) | 437 (35.0) | |
| Yes | 300 (37.3) | 505 (62.7) | 805 (64.5) | |
| Unknown | 1 (16.7) | 5 (83.3) | 6 (0.5) | |
| History of adverse pregnancy outcome | 0.020 | |||
| No | 316 (31.9) | 674 (68.1) | 990 (79.3) | |
| Yes | 63 (24.4) | 195 (75.6) | 258 (20.7) | |
| History of syphilis infection | < 0.001 | |||
| No | 267 (35.2) | 492 (64.8) | 759 (60.8) | |
| Yes | 112 (22.9) | 377 (77.1) | 489 (39.2) | |
| Time of syphilis diagnose (gestational age, weeks) | ||||
| < 28w or pre-pregnancy | 58 (6.9) | 781 (93.1) | 839 (67.2) | |
| ≥ 28w | 321 (78.5) | 88 (21.5) | 409 (32.8) | |
| Current staging of syphilis infection | 0.125 | |||
| Latent | 302 (29.9) | 708 (70.1) | 1010 (80.9) | |
| Primary / Secondary / Tertiary | 18 (24.0) | 57 (76.0) | 75 (6.0) | |
| Unknown | 59 (36.2) | 104 (63.8) | 163 (13.1) | |
| Non-treponemal serum test titer | 0.001 | |||
| < 1:8 | 297 (28.4) | 750 (71.6) | 1047 (83.9) | |
| ≥ 1:8 | 69 (39.0) | 108 (61.0) | 177 (14.2) | |
| Unknown | 13 (54.2) | 11 (45.8) | 24 (1.9) | |
| Location of diagnosing hospital | 0.002 | |||
| Urban | 107 (25.9) | 306 (74.1) | 413 (33.1) | |
| Suburban | 157 (36.4) | 274 (63.6) | 431 (34.5) | |
| Rural | 115 (28.5) | 289 (71.5) | 404 (32.4) | |
| Type of diagnosing hospital | < 0.001 | |||
| Public | 341 (29.1) | 832 (70.9) | 1173 (94.0) | |
| Private | 38 (50.7) | 37 (49.3) | 75 (6.0) | |
| Grade of diagnosing hospital | < 0.001 | |||
| Township | 122 (40.7) | 178 (59.3) | 300 (24.0) | |
| District | 103 (27.8) | 267 (72.2) | 370 (29.7) | |
| Municipal / Provincial | 154 (26.6) | 424 (73.4) | 578 (46.3) | |
Abbreviations: SD, standard deviation.
a: Chi-square tests; b: T-test;