Table 3.

Complement marker levels of Black African and White European men

	Black African		White European		P	P
	n		N		Unadjusted	Adjusted for age
Components
C1q µg/ml	85	98.5 (93.7, 103.6)	81	96.2 (90.6, 102.2)	0.551	0.791
C4 µg/ml	88	257.0 ± 74.0	97	229.0 ± 57.0	0.005	<0.001
C3 µg/ml	88	1160 ± 190.0	97	1120 ± 200.0	0.268	0.030
FB µg/ml	85	113.8 (105.4, 122.9)	81	105.8 (96.7, 115.8)	0.240	0.215
FD µg/ml	85	1.60 ± 0.94	81	1.95 ± 1.12	0.031	0.017
C5 µg/ml	85	82.3 (77.6, 87.4)	81	85.3 (79.3, 91.8)	0.473	0.838
Activation products
iC3b µg/ml	85	4.51 (3.60, 5.66)	81	2.19 (1.77, 2.71)	<0.001	<0.001
TCC µg/ml	85	13.97 (12.55, 15.54)	81	12.31 (11.13, 13.63)	0.109	0.238
Regulators
C1inh µg/ml	85	167.1 (159.9, 174.5)	81	171.3 (163.8, 179.2)	0.422	0.399
FH µg/ml	85	222.4 (205.1, 241.3)	81	243.4 (226.3, 261.9)	0.103	0.185
FHR125 µg/ml	85	49.4 (39.9, 61.1)	81	64.8 (50.1, 83.8)	0.123	0.190
FHR4 µg/ml	85	4.85 (4.52, 5.20)	81	4.80 (4.41, 5.22)	0.841	0.840
FI µg/ml	85	43.1 ± 10.7	81	42.1 ± 14.0	0.603	0.124
Properdin µg/ml	85	7.58 (7.23, 7.94)	81	7.04 (6.74, 7.36)	0.029	0.031
Clusterin µg/ml	85	203.1 (197.3, 209.0)	81	167.9 (162.0, 174.0)	<0.001	<0.001

Data presented as mean ± SD, or geometric mean (95% CIs) for transformed variables. Differences between the two ethnic groups were determined using independent samples t-tests or analysis of covariance (ANCOVA) when controlling for confounders. Non-parametric variables were log-transformed before normal tests were carried out on them. P¹ unadjusted comparison of means; P² age-adjusted comparison of means. Significant differences are highlighted in bold.