Table 4.

Associations between complement markers and metabolic health

	Black African		White European
	r	p	r	P
C3 (BA n = 88; WE n = 97)
Age*	0.403	<0.001	0.361	<0.001
BMI	0.571	<0.001	0.625	<0.001
Waist	0.585	<0.001	0.660	<0.001
HOMA2-IR*a	0.561	<0.001	0.630	<0.001
HbA1c*	0.516	<0.001	0.350	<0.001
C4 (BA n = 88; WE n = 97)
Age*	0.362	0.001	0.332	0.001
BMI	0.195	0.068	0.303	<0.001
Waist	0.234	0.029	0.382	<0.001
HOMA2-IR*a	0.200	0.156	0.339	0.011
HbA1c*	0.462	<0.001	0.240	0.018
iC3b* (BA n = 85; WE n = 81)
Age*	–0.145	0.184	0.107	0.343
BMI	–0.028	0.800	0.138	0.219
Waist	–0.068	0.537	0.197	0.081
HOMA2-IR*a	0.149	0.297	0.130	0.352
HbA1c*	–0.108	0.326	–0.173	0.124
Clusterin* (BA n = 85; WE n = 81)
Age*	–0.008	0.943	–0.003	0.976
BMI	–0.046	0.673	–0.264	0.017
Waist	–0.062	0.572	–0.290	0.009
HOMA2-IR*a	0.112	0.433	–0.240	0.083
HbA1c*	0.072	0.510	–0.190	0.090
Properdin* (BA n = 85; WE n = 81)
Age*	0.187	0.087	–0.110	0.328
BMI	0.231	0.033	0.056	0.620
Waist	0.124	0.261	–0.028	0.803
HOMA2-IR*a	0.059	0.682	–0.149	0.288
HbA1c*	-0.039	0.722	–0.389	<0.001
FD (BA n = 85; WE n = 81)
Age*	–0.169	0.123	–0.034	0.762
BMI	0.011	0.917	0.145	0.199
Waist	0.013	0.909	0.126	0.270
HOMA2-IR*a	0.128	0.370	0.113	0.419
HbA1c*	–0.240	0.027	–0.227	0.043

Correlation coefficients determined using Pearson’s correlation.

*Data were log-transformed before analysis to achieve a normal distribution.

^aData available for BA n = 52 and WE n = 55.