. Author manuscript; available in PMC: 2023 Apr 7.

Published in final edited form as: J Labelled Comp Radiopharm. 2018 Feb 5;61(3):196–227. doi: 10.1002/jlcr.3570

TABLE 4.

Radiotracers prepared from aryl(mesityl)iodonium salts: copper mediated

Entry	Target radiotracer		Precursor Structure	Labeling Technique	Labeling Conditions			Yield,^a %	Reference
Entry	Name	Structure	Precursor Structure	Labeling Technique	Solvent	°C	min	Yield,^a %	Reference
1	[¹⁸F]FDAA1106			Minimalist (1 step)	dmf	85	20	93 (60) (41 ± 3)	Zlatopolskiy et al,¹⁰⁵ Zischler et al¹³⁸
2	[¹⁸F]4-FPhe			Minimalist (2 steps)	DMF	85	20	81-92 (53-66) (56 ± 5)	Zlatopolskiy et al,¹⁰⁵ Zischler et al¹³⁸
3	[¹⁸F]6-FDA			Minimalist (2 steps)	DMF	85	20	71-94 (46)	Zlatopolskiy et al¹⁰⁵
4	[¹⁸F]FDOPA			Batch	DMF	85	20	17 ± 5	Ichiishi et al⁴¹
5	[¹⁸F]FDOPA			Batch	DMF	85	20	31 ± 3	Ichiishi et al⁴¹
6	[¹⁸F]4-FPhe			Batch	DMF	85	20	23 ± 5	Ichiishi et al⁴¹

Abbreviations: DMF, dimethylformamide; [¹⁸F]4-FPhe, [¹⁸F]l-4-fluorophenylalanine; [¹⁸F]6-FDA, [¹⁸F]6-fluorodopamine.

Values in plain type are yields before isolation. Values in bold and parentheses are yields after isolation.