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[Preprint]. 2023 Mar 27:rs.3.rs-2715993. [Version 1] doi: 10.21203/rs.3.rs-2715993/v1

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Figure 5. — (a) Cartoon of an implanted optofluidic cannula to deliver both light and fluid in the mouse brain.

(b) Histology validating implantation of optofluidic cannula targeting the left auditory cortex.

(c) System for monitoring pup retrieval behavior compatible with an optofluidic cannula.

(d) Schematic of pup retrieval behavior paradigm of virgin female mice co-housed with experienced dams comparing caged (LED Off) and uncaged (LED On) oxytocin.

(e) Initially-naive virgins reliably retrieving 2+ times <12 hours after co-housing while infused with caged oxytocin with either with the 365 nm LED on or off (LED On: 7 / 9 animals; LED Off: 3 / 12 animals), p=0.03 was determined using Fisher’s exact test (two-tailed); Error bars: means ±95% confidence intervals.

(f) Cumulative retrieval during co-housing.

* p<0.05