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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: J Allergy Clin Immunol. 2022 Oct 11:S0091-6749(22)01182-4. doi: 10.1016/j.jaci.2022.09.002

FIG 2.

FIG 2.

STAT3 GOF mutations. Seventy-two unique STAT3 variants spanned all domains of the STAT3 molecule. Red dots indicate novel patients; black dots, previously published patients. A, Alanine (Ala); C, cysteine (Cys); D, aspartic acid (Asp); E, glutamic acid (Glu); F, phenylalanine (Phe); G, glycine (Gly); H, histidine (His); I, isoleucine (Ile); K, lysine (Lys); L, leucine (Leu); M, methionine (Met); N, asparagine (Asn); P, prolie (Pro); Q, glutamine (Gln); R, arginine (Arg); S, serine (Ser); T, threonine (Thr); V, valine (Val); W, tryptophan (Trp); Y, tyrosine (Tyr).