Fig. 3. Reduced metabolic network showcasing the intersection between glutathione metabolism and arginine and proline metabolism.

Highlighted metabolites are significantly accumulated over the course of the phase change as seen in the violin plots (p-values from the linear model). Non-highlighted metabolites were not identified in the data set. In the boxplots, the center lines represent the median; box limits represent upper and lower quartiles; whiskers extend to the first or last data point that is within 1.5× the interquartile range of the box limits in the lower and upper directions respectively. Dots are values outside of 1.5× interquartile range beyond either end of the box.