Table 1.
Morphometric results and histological findings of corpus mucosa
Variables | Atrophy grade (n = 943) | Spearman correlation | |||||
---|---|---|---|---|---|---|---|
0 (n = 672) | 1 (n = 84) | 2 (n = 88) | 3 (n = 99) | r s | 95% CI | P value | |
Foveolar length (mm) | 0.29 (0.21, 0.39) | 0.32 (0.24, 0.40) | 0.38 (0.28, 0.47) | 0.39 (0.30, 0.53) | 0.231 | 0.168 to 0.292 | <.001 |
Glandular length (mm) | 0.55 (0.44, 0.68) | 0.47 (0.35, 0.61) | 0.38 (0.27, 0.49) | 0.33 (0.26, 0.46) | −0.399 | −0.453 to −0.342 | <.001 |
Musculus mucosae thickness (mm) | 0.08 (0.05, 0.12) | 0.09 (0.05, 0.13) | 0.10 (0.08, 0.16) | 0.12 (0.08, 0.19) | 0.224 | 0.161 to 0.286 | <.001 |
Total mucosal thickness (mm) | 0.95 (0.80, 1.12) | 0.91 (0.76, 1.04) | 0.92 (0.72, 1.09) | 0.86 (0.70, 1.05) | −0.114 | −0.178 to −0.048 | <.001 |
Foveolar/foveolar and glandular length ratio | 0.35 (0.28, 0.43) | 0.40 (0.33, 0.50) | 0.50 (0.39, 0.57) | 0.54 (0.45, 0.62) | 0.438 | 0.384 to 0.490 | <.001 |
Inflammation grade | 1 (1, 1) | 2 (1, 2) | 3 (2, 3) | 3 (2, 3) | 0.665 | 0.627 to 0.700 | <.001 |
Activity grade | 0 (0, 0) | 0 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0.269 | 0.207 to 0.329 | <.001 |
Metaplasia grade | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) | 3 (0, 3) | 0.600 | 0.556 to 0.641 | <.001 |
Helicobacter pylori density | 0 (0, 0) | 0 (0, 0) | 0 (0, 1) | 0 (0, 0) | 0.121 | 0.056 to 0.186 | <.001 |
Data expressed as median and interquartile range (IQR). Four grades: 0 = none or minimal, 1 = mild, 2 = moderate, and 3 = severe.
The correlation coefficient (rs) between the mucosal thickness or histological scores and atrophy degrees was calculated by Spearman rank correlation.
CI = confidence interval.