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. 2022 Apr 7;102(14):e33480. doi: 10.1097/MD.0000000000033480

Table 1.

Morphometric results and histological findings of corpus mucosa

Variables Atrophy grade (n = 943) Spearman correlation
0 (n = 672) 1 (n = 84) 2 (n = 88) 3 (n = 99) r s 95% CI P value
Foveolar length (mm) 0.29 (0.21, 0.39) 0.32 (0.24, 0.40) 0.38 (0.28, 0.47) 0.39 (0.30, 0.53) 0.231 0.168 to 0.292 <.001
Glandular length (mm) 0.55 (0.44, 0.68) 0.47 (0.35, 0.61) 0.38 (0.27, 0.49) 0.33 (0.26, 0.46) −0.399 −0.453 to −0.342 <.001
Musculus mucosae thickness (mm) 0.08 (0.05, 0.12) 0.09 (0.05, 0.13) 0.10 (0.08, 0.16) 0.12 (0.08, 0.19) 0.224 0.161 to 0.286 <.001
Total mucosal thickness (mm) 0.95 (0.80, 1.12) 0.91 (0.76, 1.04) 0.92 (0.72, 1.09) 0.86 (0.70, 1.05) −0.114 −0.178 to −0.048 <.001
Foveolar/foveolar and glandular length ratio 0.35 (0.28, 0.43) 0.40 (0.33, 0.50) 0.50 (0.39, 0.57) 0.54 (0.45, 0.62) 0.438 0.384 to 0.490 <.001
Inflammation grade 1 (1, 1) 2 (1, 2) 3 (2, 3) 3 (2, 3) 0.665 0.627 to 0.700 <.001
Activity grade 0 (0, 0) 0 (0, 1) 0 (0, 1) 0 (0, 1) 0.269 0.207 to 0.329 <.001
Metaplasia grade 0 (0, 0) 0 (0, 0) 0 (0, 0) 3 (0, 3) 0.600 0.556 to 0.641 <.001
Helicobacter pylori density 0 (0, 0) 0 (0, 0) 0 (0, 1) 0 (0, 0) 0.121 0.056 to 0.186 <.001

Data expressed as median and interquartile range (IQR). Four grades: 0 = none or minimal, 1 = mild, 2 = moderate, and 3 = severe.

The correlation coefficient (rs) between the mucosal thickness or histological scores and atrophy degrees was calculated by Spearman rank correlation.

CI = confidence interval.