Table 1.
Clinical data of patients with polycythemia vera associated with IgAN at renal biopsy.
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
| Sex | M | M | M | M | M | M | M |
| Age at biopsy (yr) | 22 | 40 | 55 | 33 | 70 | 73 | 51 |
| PV duration (mo) | 31 | 30 | 61 | 16 | 358 | 144 | 48 |
| Renal disease duration (mo) | 31 | 32 | 50 | 16 | 83 | 108 | 216 |
| Hypertension | No | Yes | Yes | No | Yes | Yes | No |
| Splenomegaly | No | Yes | No | Yes | Yes | No | No |
| Hemoglobin (g/L) | 186 | 223 | 210 | 201 | 149 | 158 | 175 |
| PLT (109/L) | 250 | 256 | 333 | 439 | 410 | 306 | 341 |
| WBC (109/L) | 6.2 | 10.9 | 9.2 | 9.7 | 8.9 | 5.2 | 5.4 |
| HCT (%) | 55.7 | 59.9 | 67 | 62.8 | 44.5 | 47.9 | 51.4 |
| Proteinuria (g/24 h) | 11.76 | 9.63 | 2.1 | 1.25 | 2.06 | 0.73 | 0.25 |
| Urinary microscopic hematuria (10,000 cells/mL) | 1 | 570 | 95 | 72 | 12 | 22 | 10 |
| Serum albumin (g/L) | 23.2 | 31.4 | 38.5 | 40.8 | 45.7 | 46.5 | 46 |
| Serum creatinine (mg/dL) | 1.09 | 1.05 | 1.91 | 0.75 | 1.19 | 1.28 | 0.95 |
| eGFR (mL/min/1.73 m2) at biopsy | 98.89 | 84.04 | 37.95 | 130.77 | 65.35 | 59.3 | 90.99 |
| Bone marrow | + | + | + | + | + | + | + |
| JAK2V617F | − | − | + | + | ND | − | ND |
| BCR-ABL | − | − | − | − | ND | − | ND |
HCT = hematocrit, M = male, PLT = platelet, pv = polycythemia vera, WBC = white blood cell count.