Figure 5.

Path models. (A) The first principal component of the SD variables (SD_component) mediates the effect of the blood volume variables (blood_component) on delayed infarct volumes (DCI_component). (B) Path model treating blood_component and the first principal component of the DSA variables (DSA_component) as extrinsic variables and SD_component as mediator variable. (C) Path model including IVH into the analysis. There were two paths, one from blood_component to DCI_component with SD_component as mediator variable, and one from IVH to DCI_component with DSA_component as mediator variable. The numbers at the arrows represent the pc and the P-values (the corresponding z-values are found in the text). P-values of path models use the standard normal distribution for quotients of unstandardised pc and their standard errors and Chi-square tests for model fit with degrees of freedom equal to ‘number of parameters saturated model minus number of parameters actual model’.⁷⁸