. 2023 Mar 22;5(2):fcad080. doi: 10.1093/braincomms/fcad080

Table 3.

Spearman correlations between region-specific blood volumes and potential mediators of delayed infarction

Statistical analysis	Variable	Spearman coefficient	P-value	Number of patients
Association analysis with blood_convex	PTDDD_delayed	0.29	0.001	136
	peak_SD-delayed	0.25	0.003	136
	peak_{isoSD-delayed}	0.25	0.003	136
	peak_{clusSD-delayed}	0.24	0.005	136
	mbfv_ACA	0.11	0.265	112
	mbfv_MCA	0.21	0.020	128
	mbfv_PCA	0.08	0.442	98
	DSA_A1	−0.01	0.915	103
	DSA_A2	−0.14	0.165	104
	DSA_M1	0.10	0.302	105
	DSA_M2	0.24	0.014	105
	DSA_P1	0.05	0.633	91
	DSA_P2	0.02	0.842	90
Association analysis with blood_inter	PTDDD_delayed	0.08	0.342	136
	peak_SD-delayed	0.04	0.647	136
	peak_{isoSD-delayed}	0.05	0.542	136
	peak_{clusSD-delayed}	0.03	0.716	136
	mbfv_ACA	−0.08	0.420	112
	mbfv_MCA	0.00	0.993	128
	mbfv_PCA	0.13	0.215	98
	DSA_A1	0.21	0.032	103
	DSA_A2	0.31	0.001	104
	DSA_M1	0.09	0.345	105
	DSA_M2	−0.07	0.454	105
	DSA_P1	−0.01	0.957	91
	DSA_P2	0.05	0.677	90
Association analysis with blood_Sylvian	PTDDD_delayed	0.28	0.001	136
	peak_SD-delayed	0.25	0.004	136
	peak_{isoSD-delayed}	0.30	<0.001	136
	peak_{clusSD-delayed}	0.21	0.016	136
	mbfv_ACA	−0.02	0.843	112
	mbfv_MCA	0.11	0.215	128
	mbfv_PCA	0.01	0.930	98
	DSA_A1	−0.06	0.560	103
	DSA_A2	−0.11	0.281	104
	DSA_M1	−0.04	0.654	105
	DSA_M2	0.15	0.126	105
	DSA_P1	0.05	0.663	91
	DSA_P2	0.07	0.514	90
Association analysis with blood_basal	PTDDD_delayed	0.14	0.100	136
	peak_SD-delayed	0.09	0.292	136
	peak_{isoSD-delayed}	0.15	0.088	136
	peak_{clusSD-delayed}	0.08	0.331	136
	mbfv_ACA	−0.07	0.491	112
	mbfv_MCA	0.06	0.525	128
	mbfv_PCA	0.16	0.113	98
	DSA_A1	0.16	0.097	103
	DSA_A2	0.20	0.043	104
	DSA_M1	0.03	0.761	105
	DSA_M2	−0.02	0.876	105
	DSA_P1	0.08	0.453	91
	DSA_P2	0.16	0.125	90
Association analysis with ICH	PTDDD_delayed	0.10	0.274	136
	peak_SD-delayed	0.07	0.413	136
	peak_{isoSD-delayed}	0.04	0.622	136
	peak_{clusSD-delayed}	0.06	0.500	136
	mbfv_ACA	0.08	0.413	112
	mbfv_MCA	−0.03	0.703	128
	mbfv_PCA	0.03	0.806	98
	DSA_A1	0.08	0.419	103
	DSA_A2	0.06	0.548	104
	DSA_M1	0.14	0.157	105
	DSA_M2	0.04	0.697	105
	DSA_P1	0.08	0.450	91
	DSA_P2	0.04	0.691	90
Association analysis with IVH	PTDDD_delayed	0.05	0.551	136
	peak_SD-delayed	0.00	0.977	136
	peak_{isoSD-delayed}	−0.03	0.734	136
	peak_{clusSD-delayed}	0.03	0.718	136
	mbfv_ACA	0.10	0.290	112
	mbfv_MCA	0.08	0.399	128
	mbfv_PCA	0.16	0.127	98
	DSA_A1	0.19	0.058	103
	DSA_A2	0.35	<0.001	104
	DSA_M1	0.17	0.088	105
	DSA_M2	0.20	0.041	105
	DSA_P1	0.31	0.003	91
	DSA_P2	0.26	0.015	90

Statistically significant values are marked in bold.

All given data only refer to the hemisphere ipsilateral to the subdural electrodes. blood_basal = subarachnoid blood volume in the basal cisterns; blood_convex = subarachnoid blood volume on the cerebral convexity; blood_inter = subarachnoid blood volume in the interhemispheric fissure; blood_Sylvian = subarachnoid blood volume in the Sylvian fissure; DSA = digital subtraction angiography [A1, A2, M1, M2, P1, P2 = first and second segments of anterior cerebral artery (ACA), middle cerebral artery (MCA) and posterior cerebral artery (PCA) ipsilateral to the subdural electrodes]; ICH = intracerebral haemorrhage; IVH = intraventricular haemorrhage; mbfv_ACA = transcranial Doppler-sonography (TCD)-determined peak mean blood flow velocity of ACA; mbfv_MCA = TCD-determined peak mean blood flow velocity of MCA; mbfv_PCA = TCD-determined peak mean blood flow velocity of PCA; peak_{clusSD-delayed} = peak number of clustered spreading depolarizations (SD) of a recording day during the delayed period between the early post-intervention neuroimage and the late neuroimage after completion of neuromonitoring (clustered SD = SD that occurred less than 1 h apart from the previous SD); peak_{isoSD-delayed} = peak number of isoelectric SDs of a recording day during the delayed period (isoelectric SD = SD in electrically inactive tissue); peak_SD-delayed = peak number of SDs of any type of a recording day during the delayed period; PTDDD_delayed = peak value of a recording day for the total (cumulative) SD-induced depression durations during the delayed period.