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. 2023 Mar 22;5(2):fcad080. doi: 10.1093/braincomms/fcad080

Table 4.

Spearman correlations between potential mediators and delayed cortical infarct volumes

Statistical analysis Variable Spearman coefficient P-value Number of patients
Association analysis with DCIACA PTDDDdelayed 0.19 0.024 136
peakSD-delayed 0.18 0.042 136
peakisoSD-delayed 0.23 0.006 136
peakclusSD-delayed 0.18 0.033 136
mbfvACA 0.15 0.126 112
mbfvMCA 0.16 0.076 128
mbfvPCA 0.01 0.936 98
DSAA1 0.23 0.017 103
DSAA2 0.33 0.001 104
DSAM1 0.22 0.025 105
DSAM2 0.21 0.031 105
DSAP1 0.33 0.002 91
DSAP2 0.31 0.003 90
Association analysis with DCIMCA PTDDDdelayed 0.55 <0.001 136
peakSD-delayed 0.47 <0.001 136
peakisoSD-delayed 0.50 <0.001 136
peakclusSD-delayed 0.46 <0.001 136
mbfvACA 0.24 0.010 112
mbfvMCA 0.20 0.021 128
mbfvPCA 0.22 0.031 98
DSAA1 0.21 0.030 103
DSAA2 0.10 0.318 104
DSAM1 0.25 0.012 105
DSAM2 0.16 0.099 105
DSAP1 0.08 0.456 91
DSAP2 0.12 0.257 90
Association analysis with DCIPCA PTDDDdelayed 0.22 0.012 136
peakSD-delayed 0.26 0.003 136
peakisoSD-delayed 0.24 0.006 136
peakclusSD-delayed 0.19 0.031 136
mbfvACA 0.32 <0.001 112
mbfvMCA 0.12 0.172 128
mbfvPCA 0.19 0.056 98
DSAA1 0.11 0.265 103
DSAA2 0.15 0.122 104
DSAM1 0.06 0.563 105
DSAM2 −0.02 0.874 105
DSAP1 −0.02 0.868 91
DSAP2 0.04 0.700 90

Statistically significant values are marked in bold.

All given data only refer to the hemisphere ipsilateral to the subdural electrodes. DCIACA = delayed infarct volume in the territory of the anterior cerebral artery; DCIMCA = delayed infarct volume in the territory of the middle cerebral artery; DCIPCA = delayed infarct volume in the territory of the posterior cerebral artery; DSA = digital subtraction angiography (A1, A2, M1, M2, P1, P2 = first and second segments of ACA, MCA and PCA ipsilateral to the subdural electrodes); ICH = intracerebral haemorrhage; IVH = intraventricular haemorrhage; mbfvACA = transcranial Doppler-sonography (TCD)-determined peak mean blood flow velocity of ACA; mbfvMCA = TCD-determined peak mean blood flow velocity of MCA; mbfvPCA = TCD-determined peak mean blood flow velocity of PCA; peakclusSD-delayed = peak number of clustered spreading depolarizations (SD) of a recording day during the delayed period between the early post-intervention neuroimage and the late neuroimage after completion of neuromonitoring (clustered SD = SD that occurred less than 1 h apart from the previous SD); peakisoSD-delayed = peak number of isoelectric SDs of a recording day during the delayed period (isoelectric SD = SD in electrically inactive tissue); peakSD-delayed = peak number of SDs of any type of a recording day during the delayed period; PTDDDdelayed = peak value of a recording day for the total (cumulative) SD-induced depression durations during the delayed period.