Table 3.
Clinical features of HAE patients
| Clinical features | Findings |
|---|---|
| Attacks per year since the diagnosis of HAE (n = 10) | |
| 1–5 | 4 |
| 6–11 | 2 |
| 12–24 | 0 |
| > 24 | 4 |
| Frequency of attacks in the last 12 monthsa (n = 9) | |
| Mild | 4 |
| Moderate | 1 |
| Severe | 4 |
| Swelling location (n = 10) | |
| Skin | 10 |
| Lips | 9 |
| Tongue | 8 |
| Abdomen | 8 |
| Larynx | 8 |
| Urogenital area | 3 |
| Prodrome (n = 9) | |
| Tiredness | 8 |
| Paraesthesia/pain | 8 |
| Abdominal pain | 8 |
| Nausea | 3 |
| Erythema marginatum | 2 |
| Trigger factors (n = 6) | |
| Stress | 4 |
| Trauma | 2 |
| Surgical/dental manipulations | 2 |
| Infection | 1 |
| Menstruation | 1 |
aSevere—if the patient had experienced 12 or more attacks during the last 12 months, moderate—4 − 11 attacks, mild—1 − 3 attacks, and asymptomatic—no attacks