Skip to main content
. 2023 Apr 8;13(4):e1233. doi: 10.1002/ctm2.1233

FIGURE 6.

FIGURE 6

Reduced peri‐lesional presence of wound healing macrophages under treatment with anti‐β7 integrin antibody. Peri‐lesional co‐expression of Cd68 and Cd163 (A), F4/80 and Cd206 (B), F4/80 and Arg1 (C) and F4/80 and inducible nitric oxide synthase (iNos) (D) in intestinal wound areas of C57BL/6J mice treated either with anti‐β7 integrin antibody (n = 14), anti‐α4β7 integrin antibody (n = 11) or isotype control (n = 13). Tissue was collected 5 days after wounding. Representative (left) and quantitative immunohistochemistry (right); scale bars 50 µm (upper panels), 25 µm (lower panels); HPF, high‐power field. Outliers were identified using the ROU test. *p < 0.05; ***p < 0.001; ****p < 0.0001.