Table 4.
Effect of the studied variant of NOS3 gene on clinical parameters in patients with COVID-19.
| Parameters |
NOS3 rs61722009 |
Results of the statistical analysis | ||
|---|---|---|---|---|
| 4bb | 4ba | 4aa | ||
| SpO2/FiO2 1d | 126.9 ± 65.6 | 116.5 ± 40.7 | 220.1 ± 122.3 | p = 0.017 |
| SpO2/FiO2 2d | 157.2 ± 106.1 | 124.0 ± 40.7 | 285.±157.9 | p = 0.03 |
| BE 1d, mmol/l | 2.5 ± 3.7 | 5.8 ± 8.0 | −8.7 ± 2.1 | p = 0.037 |
| SBC 2d, mmol/l | 26.1 ± 3.1 | 24.4 ± 4.7 | 13.9 ± 2.8 | p = 0.044 |
| K 1d, mmol/l | 4.6 ± 0.8 | 4.2 ± 0.7 | 3.4 ± 0.5 | p = 0.009 |
| Na 2d, mmol/l | 143.3 ± 6.7 | 143.7 ± 6.5 | 136.7 ± 2.5 | p = 0.048 |
| CRP 2d, mg/l | 21.9 ± 12.6 | 32.1 ± 15.9 | 74.6 ± 8.2 | p = 0.002 |
| Bilirubin total 1d, μmol/l | 17.9 ± 28.4 | 17.6 ± 24.5 | 21.4 ± 12.0 | p = 0.033 |
1d, 2d – day after hospitalization.
BE – basis excess.
SBC– standard bicarbonate.
CRP – С-reactive protein.