Figure-1.

(a) Schematic representation of the different treatment approaches. Antiviral activity assays of flavonoids were performed according to the virus life cycle and steps of infection, including pre-compounds treatment, attachment, penetration, post-viral infection and virucidal assays. (b) Experimental timelines and antiviral effects in the time-of-addition assay. The feline infectious peritonitis virus-infected Crandell–Rees feline kidney cells were treated with the compounds at different time points after post-viral infection (0, 2, 4, 6 and 8 h post-infection; green arrows).