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. 2023 Apr 8;14(4):259. doi: 10.1038/s41419-023-05732-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Representative IHC images of IRAK1 protein in human glioma tissues and brain benign tumor tissues. 200×: scale bar = 100 μm; 400×: scale bar = 50 μm. b Kaplan-Meier survival plot for overall survival grouped by IRAK1 expression in 52 glioma patients (p = 0.0006). c IRAK1 mRNA expression profiling data from TCGA and GTEx databases analyzed by the GEPIA webserver (Non-tumor, n = 207; LGG, n = 518; GBM, n = 163; *p < 0.05). d IRAK1 expression analysis for non-tumor and glioma samples in Rembrandt database (****p < 0.0001). The correlation between IRAK1 and OS in glioma patients from TCGA (e) and Rembrandt (f) cohorts, with the hazard ratio (HR) and p values displayed.