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. 2023 Apr 8;13:119. doi: 10.1038/s41398-023-02414-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Females: locomotion plots comparing vehicle and psilocin groups at each time point. Data points are mean time in seconds +/− S.E.M. B Females: time spent rearing comparing vehicle and psilocin groups at each time point. Data points are mean time in seconds +/− S.E.M. C Males: locomotion plots comparing vehicle and psilocin groups at each time point. Data points are mean time in seconds +/− S.E.M. D Males: time spent rearing comparing vehicle and psilocin groups at each time point. Data points are mean time in seconds +/− S.E.M. E Females threat responding behavior. First figure is showing percentage of subjects that darted following air-puff administration. Second figure is showing the percentage of animals that remained immobile following air-puff. Third and fourth figure are pie charts showing the percentage of animals that darted vs. remained immobile F Males threat responding behavior: First figure is showing percentage of subjects that darted following air-puff administration. Second figure is showing the percentage of subject that remained immobile following air-puff. Third and fourth figure are pie charts showing the percentage of animals that darted vs. remained immobile. G Male vehicle passive responders (remained immobile) group: First figure shows air-puff trace plots of changes in CeA fluorescence following exposure to a 500 ms air-puff at 85 psi. Data points represent group averages within 500 ms binned window +/− S.E.M.; second figure is a histogram showing differences in the mean peak ΔF/F value for each group +/− S.E.M following air-puff administration. Data points reflect each individual subject within the corresponding subgroup. H Male psilocin passive responders (remained immobile) group: First figure shows air-puff trace plots of changes in CeA fluorescence following exposure to a 500 ms air-puff at 85 psi. Data points represent group averages within 500 ms binned window +/− S.E.M. Second figure is a histogram showing differences in the mean peak ΔF/F value for each group +/− S.E.M following air-puff administration. Data points reflect each individual subject within the corresponding subgroup. I Male vehicle active responders (darted) group: First figure shows air-puff trace plots of changes in CeA fluorescence following exposure to a 500 ms air-puff at 85 psi. Data points represent group averages within 500 ms binned window +/− S.E.M. Second figure is a histogram showing differences in the mean peak ΔF/F value for each group +/− S.E.M following air-puff administration. Data points reflect each individual subject within the corresponding subgroup. J Male psilocin active responders (darted) group: First figure shows air-puff trace plots of changes in CeA fluorescence following exposure to a 500 ms air-puff at 85 psi. Data points represent group averages within 500 ms binned window +/− S.E.M. Second figure is a histogram showing differences in the mean peak ΔF/F value for each group +/− S.E.M following air-puff administration. Data points reflect each individual subject within the corresponding subgroup. *p < 0.05, **p < 0.01.