Table 1. Studies on the Effect of Blue Light Therapy on Wound Healing in Humans .

First Author, Publication Year	Probable Disease; Type and Location of Wound	BLT Parameters	Main Results and/or Conclusions	Methodological Quality of Study
Fraccalvieri, 202221	90 Patients with vascular or non-healing surgical dehiscence ulcers	BLT, range of wavelength between 410-430 nm, 60 seconds, 120 mW/cm2; 7.2 J/cm2, weekly treatment.	BLT plus standard care of ulcers accelerated new epidermal cell formation in ulcers of lower limbs by 2.5 months.	50%; randomization and blinding were not mentioned.
Dini, 202122	20 Patients with ulcers (12 patients with venous foot ulcers, 6 patients with skin vasculitis, 2 patients with traumatic ulcers) resistant to regular therapy.	BLT, range of wavelength between 400 - 430 nm, 120 mW/cm2.	BLT encouraged wound healing, improved WBS, and decreased soreness in patients.	50%; randomization and blinding were not mentioned.

All light was radiated from LED devices.

Abbreviations: WBS, wound bed score; BLT, blue light therapy.