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. Author manuscript; available in PMC: 2023 Apr 9.
Published in final edited form as: J Am Chem Soc. 2022 Mar 15;144(12):5214–5225. doi: 10.1021/jacs.2c00224

Figure 3.

Figure 3.

Convergent synthesis of antiviral drugs using reversible phosphorylases from nucleotide salvage pathways. DERA: deoxyribose 5-phosphate aldolase; PPM: phosphopentomutase; PNP: purine nucleotide phosphorylase; MTR kinase: 5-S-methylthioribose kinase; UP: uridine phosphorylase; PO: pyruvate oxidase; AcK: acetate kinase; HMDS: hexamethyldisilazane.