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. Author manuscript; available in PMC: 2023 Apr 9.
Published in final edited form as: FASEB J. 2021 Aug;35(8):e21785. doi: 10.1096/fj.202100047R

FIGURE 4.

FIGURE 4

Renal ROS production and NLRP3 inflammasome activation in ASLN mice. A, ROS. B, NF-κB activity. C, mRNA levels of NLRP3, caspase-1, IL-1β. D, Protein levels NLRP3, caspase-1 and IL-1β; (E-H) Semiquantitative analysis. I, Caspase-1 activity. Data are presented as means ± SEM with seven mice per group. ASLN, accelerated, severe lupus nephritis; Cf-02, a novel benzamide-linked small molecule; ROS, reactive oxygen species. **P < .01, ***P < .005 and ****P < .001. #Not detectable. ns, no significant difference