Sn-RNA-seq |
Cynomolgus monkey |
Eight young and aged CA1, CA3, and DG |
8 000 nuclei |
12 clusters |
10x Genomics |
Yes |
Neural transiently amplifying progenitor cell and microglia were most affected by aging |
Zhang et al., 2021 |
Sn-RNA-seq |
Human |
38 human post-mortem hippocampi |
32 103 nuclei |
14 clusters |
SPLiT-Seq |
Yes |
Novel candidate gene STMN1 in human immature neurons |
Zhou et al., 2022 |
Sn-RNA-seq Sc-ATAC-seq |
Human,macaque |
13 macaque and four human donor hippocampi |
132 524 nuclei |
13 clusters |
10x Genomics |
Yes for both |
ETNPPL as a primate-specific NSC marker. STMN1 and STMN2 as immature neuronal markers in primates |
Wang et al., 2022 |
Sc-RNA-seq |
Macaque |
Eight adult macaque hippocampi |
207 785 cells |
34 clusters |
10x Genomics |
Yes |
HMGB2 as a novel intermediate progenitor cell marker |
Hao et al., 2022 |
Sn-RNA-seq |
Human, macaque, pig |
Human post-mortem DG, CA2–CA4, CA1, Sub, and EC |
219 058 nuclei |
69 Clusters |
10x Genomics |
Yes for macaques,No for humans |
METTL7B-defined subregion-specific excitatory neurons and astrocytes in primates |
Franjic et al., 2022 |