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. 2023 Mar 27;14:1022090. doi: 10.3389/fphar.2023.1022090

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Copyright © 2023 Shao, Bao, Davies Forsman, Paues, Werngren, Niward, Schön, Bruchfeld, Alffenaar and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of bedaquiline exposure and susceptibility of Mycobacterium tuberculosis isolates respectively in participants with different treatment outcomes in the validation cohort. MIC: minimum inhibitory concentration; C_max: maximum drug concentration; C_min: minimum drug concentration; AUC_0-24h: area under drug concentration-time curve over the last 24 h dosing interval. Mann-Whitney U test was applied for comparison.