Table 3.
Univariate and multivariate analysis of risk factors for overall survival in training cohort.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| FPR ≥0.29 | 2.356 | 1.395-3.981 | 0.001 | 2.592 | 1.462-4.595 | 0.001 |
| TNM stage | ||||||
| II | 1.494 | 1.010-2.211 | 0.045 | 1.531 | 1.007-2.328 | 0.046 |
| III | 2.359 | 0.726-7.669 | 0.154 | 2.294 | 0.692-7.603 | 0.175 |
| CONUT ≥4 | 2.626 | 1.355-5.091 | 0.004 | 2.462 | 1.187-5.105 | 0.015 |
| CA199 ≥37U/ml | 1.526 | 0.994-2.344 | 0.054 | 1.648 | 1.022-2.658 | 0.031 |
| CEA ≥5ng/ml | 1.960 | 1.308-2.936 | 0.001 | 1.958 | 1.268-3.024 | 0.002 |
HR, hazard ratio; CI, confidence interval; FPR, fibrinogen/prealbumin ratio; TNM, tumor node metastasis; CONUT, controlling nutritional status; CA, carbohydrate antigen; CEA, carcinoembryonic antigen.