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. 2023 Mar 27;14:1136408. doi: 10.3389/fneur.2023.1136408

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Copyright © 2023 Churchill, Roudaia, Chen, Gilboa, Sekuler, Ji, Gao, Lin, Jegatheesan, Masellis, Goubran, Rabin, Lam, Cheng, Fowler, Heyn, Black, MacIntosh, Graham and Schweizer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Altered network functional connectivity for individuals with COVID-19 relative to controls. (A) significant connections are depicted via lines connecting regions of interest (ROIs), with warm colors indicating increased connectivity for the COVID-19 group, and cool colors denoting decreased connectivity; line colors denote the strength of effect in terms of bootstrap ratio (BSR) and node sizes denote the number of significant connections. (B) heatmap showing the percentage of significant connections that occur between a given pair of lobes; a ‘*’ denotes significantly elevated connections for the lobe pair. (C) scatterplot showing mean connectivity values within regions of significant decrease, plotted for individuals in the COVID-19 and control groups; boxplots denote group means and 95%CIs of the mean.