TABLE 1.
Baseline characteristics of the population.
| Total | Prophylaxis group | Endoscopy‐driven group | p values | |
|---|---|---|---|---|
| (n = 195) | (n = 61) | |||
| (n = 134) | ||||
| Females, n (%) | 89 (45.6) | 27 (44.3) | 62 (46.3) | 0.92 |
| Median age at surgery, years (IQR) | 35 (25–47) | 31 (23.5–41) | 28.5 (26.5–50) | 0.004 |
| Median disease duration at surgery, years (IQR) | 5 (1–12) | 6 (2–13.5) | 5 (1–5) | 0.31 |
| Montreal A n (%) | ||||
| A1 | 27 (13.8) | 12 (19.7) | 15 (11.2) | 0.17 |
| A2 | 113 (57.9) | 42 (68.8) | 71 (53.0) | 0.05 |
| A3 | 55 (28.2) | 7 (11.5) | 48 (35.8) | 0.001 |
| Montreal B n (%) | ||||
| B1 | 13 (6.7) | 2 (3.3) | 11 (8.2) | 0.33 |
| B2 | 94 (48.2) | 35 (57.4) | 59 (49.3) | 0.11 |
| B3 | 88 (45.1) | 24 (39.3) | 64 (42.5) | 0.35 |
| Montreal L n (%) | ||||
| L1 | 94 (48.2) | 25 (41.0) | 69 (51.5) | 0.23 |
| L2 | 6 (3.1) | 3 (4.9) | 3 (2.2) | 0.58 |
| L3 | 95 (48.7) | 33 (54.1) | 62 (46.3) | 0.39 |
| Experienced to biological agents, n (%) | 70 (35.9) | 26 (42.6) | 44 (32.8) | 0.25 |
| Active smokers, n (%) | 67 (34.4) | 18 (29.5) | 49 (36.6) | 0.42 |
| Quit smoking at surgery, n (%) | 6 (3.1) | 0 (0.0) | 6 (4.5) | 0.42 |
| Risk factors for POR n (%) | ||||
| Active smoker after surgery | 61 (31.3) | 18 (29.5) | 43 (32.1) | 0.85 |
| Penetrating disease | 88 (45.1) | 24 (39.3) | 64 (47.8) | 0.35 |
| Previous resection | 25 (12.8) | 10 (16.4) | 15 (11.2) | 0.44 |
| History of perianal disease | 14 (7.2) | 7 (11.5) | 7 (5.2) | 0.20 |
| Large resection (>50 cm) | 7 (3.6) | 2 (3.3) | 5 (3.7) | 0.80 |
Abbreviations: IQR, interquartile range; POR, postoperative recurrence.