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. 2023 Mar 27;13:1157789. doi: 10.3389/fonc.2023.1157789

Table 2.

Univariate analyses result for disease-free survival.

Univariate analysis
N=38 Hazard ratio 95% CI P value
Age
 ≤ 60
 > 60
21
17
4.6
1
0.79-87.5 0.16
Tumor size
 T1a/T1b
 T1c
10
28
1
0.81
0.18-5.8 0.80
Surgery
 Lumpectomy
 Mastectomy
22
16
1
2.3
0.50-11.6 0.29
Adjuvant chemotherapy
 Yes
 No
24
14
1
3.7
0.74-17.1 0.11
Adjuvant therapy
 Yes
 No
27
11
1
7.4
1.6-37.8 0.0096*
Histological grade
 1/2
 3
9
29
1
0.54
0.13-2.7 0.41
Nuclear grade
 1/2
 3
7
31
1
0.12
0.023-0.54 0.0055*
Estrogen receptor
 0
 less than 1%
35
3
1
2.1
0.11-12.7 0.48
Progesterone receptor
 0
 less than 1%
34
4
1
1.2
0.064-7.1 0.86
HER2
 0
 1+/2+ and ISH negative
28
10
1
9.0
1.9-62.8 0.0090*

Of the 42 patients with Stage I TNBC, 38 were analyzed, excluding four patients whose recurrence time was unclear in the medical records.

The reference for the hazard ratio for each item was set at 1. Factors with significant differences are indicated by asterisks. Patients were divided into HER2-0 or HER2-low (1+/2+ and ISH negative) according to HER2 status. HR, hazard ratio; CI, confidence interval.