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. 2023 Mar 15;12(2):e220134. doi: 10.1530/ETJ-22-0134

Table 4.

The diagnostic sensitivity and specificity of suspicious ultrasound characteristics for predicting thyroid cancer. Comparison with the previously published data (25, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49).

Sensitivity (%) Specificity (%)
Present study Literature – median (range) Present study Literature – median (range)
Hypoechoic 80.2% (264/329) 65.4% (20.0–100.0) 46.6% (248/532) 64.6% (43.4–92.0)
Very hypoechoic 37.4% (123/329) 17.4% (14.2–41.4) 87.8% (467/532) 97.1% (92.2–97.1)
Microcalcifications 42.2% (139/329) 36.9% (12.5–55.8) 82.9% (441/532) 91.6% (12.1–98.0)
Irregular margins 37.4% (123/329) 44.2% (13.0–48.3) 88.3% (470/532) 90.0% (69.1–98.4)
Extrathyroidal extension 26.7% (88/329) 20.8% (one study) 95.9% (510/532) 97.5% (one study)