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. 2023 Apr 3;13(4):e065215. doi: 10.1136/bmjopen-2022-065215

Table 3.

Associations between children factors and caregiver burden

Factor Measure factor Outcome caregiver burden Bivariate analysis Bivariate association r/t/F/β/Z/H/X2 Multivariate association
β/b (95% CI)
N Ref
Demographics Age Years VQ burden P ns 75 8
Years ZBI P or S ns 101 12
Years ZBI ns 69 14
Years CDS S ns 209 21
Years CDS R ns 375 23
1–5/6–12/>12 years old ZBI P or S ns 109 15
Years ZBI U ns 1190 19
Gender Male/female ZBI ns 69 14
Male child CDS T 3.02** 0.18** (1.56 to 8.34) 209 21
Male child CDS R 3.60* 3.50* (−) 375 23
Male/female CBS P or S ns 109 15
Going to nursery/school Yes/no ZBI U ns 1190 19
Residence Urban/rural ZBI U nr**** 1190 19
Birth order 1st/2nd/3rd or greater CDS A ns 209 21
First/or not ZBI U ns 1190 19
No of children 3 or higher ZBI ns 69 14
1/2/3 CDS R ns 375 23
1/2/3/4 or more ZBI P or S 0.20* 109 15
1/or not ZBI U ns 1190 19
No of disabled children 1/or not ZBI P or S ns 109 15
Body mass index BMI ZBI P or S ns 101 12
Disease related Type of CP 5 types CDS A 3.15* 209 21
Spastic quadriplegia CDS R 10.62*** 375 23
Severity of illness GMFCS ZBI P or S 0.30** 101 12
Severity of illness scale ZBI 0.29* (nr) 69 14
GMFCS-ER CDS A 6.87*** 0.29*** (4.42 to 11.23) 209 21
nr ZBI 0.28* (0.04 to 0.35) 62 17
3 levels ZBI H nr** ns 1190 19
Tube/intravenous nutrition Yes/no ZBI C nr* ns 1190 19
Aetiology 7 types CDS A 2.49* 209 21
Additional physical illness Absent/present ZBI ns 69 14
Associated conditions 0/1/2/3/4 or more CDS A 3.21* 209 21
0/1 or more CDS R 12.75*** ns 375 23
Functional impairments No of functional deficits  CDS R 3.97*** 2.64*** (nr) 375 23
Behavioural functioning Functional status FIM ZBI P or S ns 109 15
Behavioural problems SDQ BM nr 0.24* 0.29** 93 25
SDQ DPC burden nr 0.38**** 0.27** (0.06 to 1.43) 94 27
Overall health Quality of life KIDSCREEN-10 BM nr ns 93 25
PedsQL ZBI P 0.40*** 120 16
Social environment Social support SSSS BM nr ns −0.19* (nr) 93 25
Environment Space for child locomotion ZBI P nr* 21 18

****p<0.0001, ***p<0.001, **p<0.01, *p<0.05.

A, one-way analysis of variance (ANOVA); BMI, Body Mass Index; C, chi-squared test; CP, cerebral palsy; FIM, Functional Independence Measure; GMFCS, Gross Motor Function Classification System; GMFCS-ER, Gross Motor Function Classification System–Expanded and Revised; H, Kruskal-Wallis H; KIDSCREEN-10, The shortest version of Kidscreen questionnaires; nr, not reported; ns, not significant; P, Pearson correlation coefficient; PedsQL, Pediatric Quality of Life 4.0 Generic Core Scales; R, univariate regression analysis; S, Spearman’s linear correlation coefficient/Spearman’s Rho correlation; SDQ, Strengths and Difficulties Questionnaire; SSSS, Satisfaction with social support scale for children and adolescents; T, independent Student’s t-test; U, Mann-Whitney U test.