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. 2023 Apr 6;9(2):e002923. doi: 10.1136/rmdopen-2022-002923

Table 1.

Baseline characteristics and treatments of patients with GCA

(N=65)
Age, mean (SD) 70.8 (9.2)
Female sex 44 (67.7)
Biopsy-proven disease 40 (61.5)
Imaging-proven disease* 21 (32.3)
New-onset disease at TCZ initiation† 27 (41.5)
Initial TCZ treatment
 4 mg/kg intravenously monthly 2 (3.1)
 8 mg/kg intravenously monthly 13 (22.0)
 162 mg subcutaneously every 2 weeks 6 (9.2)
 162 mg subcutaneously weekly 44 (67.7)
Use of other immunosuppressants for GCA
 Concurrent with TCZ 2 (3.1)‡
 Previous to TCZ 8 (12.3)§
On prednisone at TCZ initiation 65 (100)
Daily prednisone dose (mg) at TCZ initiation, mean (SD) 33.9 (21.5)
Patients receiving >1 TCZ course 13 (20.0)
Duration of first TCZ course (years), mean (SD) 1.9 (1.1)
Total duration of TCZ treatment (years), mean (SD) 2.2 (1.6)¶

Values represent number and (%) unless otherwise specified.

*Ultrasound, CT angiography, MR angiography or positron emission tomography showing arterial lesions suggestive of vasculitis.

†TCZ started within 12 weeks of GCA diagnosis without preceding disease flare.

‡Methotrexate in both cases.

§Including methotrexate, cyclophosphamide, ustekinumab, abatacept, tofacitinib and secukinumab.

¶Aggregated time on TCZ for patients who received more than one TCZ course.

GCA, giant cell arteritis; TCZ, tocilizumab.