Table 1.
Characteristic | Tagliati (2000) 11 | Slee (2006) 12 | Oliviera (2018) 1 | Jang (2013) 10 | Asada (2007) 14 |
---|---|---|---|---|---|
Clinical diagnosis | Idiopathic Parkinson's disease | Sporadic Creutzfeldt‐Jakob disease | Dementia with Lewy Bodies | Juvenile parkinsonism | Parkinsonism |
Levodopa response | Partial | n/a | No | No | No |
Pyramidal signs | Present | Absent | Absent | Absent | Present |
Cognitive impairment | Present | Present | Present | Present | Absent |
Sphincter disturbance | Urinary urgency | Urinary incontinence | Absent | Absent | n/a |
Falls < 3y from onset | Yes | No | Yes | No | Yes |
MR imaging findings | T2 hyperintensity in left temporal lobe and bilateral thalami | Symmetrical T2 hyperintensity of the thalami, lentiform nuclei, heads of the caudate nuclei. | Diffuse T2 hyperintensity with focal ring‐enhancing nodules | Left parietal T2 high signal |
Extensive bilateral diffuse T2 high‐intensity lesions in fronto‐parietal white matter T2 hypointensity in left putamen |
Gliomatosis pathology distribution | Pons, midbrain, basal ganglia, amygdala, cortex | Right temporal lobe (biopsy) | Identified on brain biopsy | Identified on brain biopsy | Cerebral white matter (biopsy) |