Table 2.
Comparison between the current case and previously reported case of diffuse glioma mimicking multiple system atrophy (MSA)
| Characteristics | Molho et al 13 | Current case |
|---|---|---|
| Age of onset (y) | 82 | 70 |
| Levodopa response | Absent | Partial |
| Pyramidal signs | Present | Present |
| Cognitive impairment | Present | Present |
| Sphincter disturbance |
Urinary urgency Erectile dysfunction |
Urinary incontinence Erectile dysfunction |
| Falls < 3y from onset | Present | Present |
| Cerebellar signs | Gait ataxia |
Nystagmus Limb and gait ataxia |
| Duration until death (m) | 48 | 84 |
| MRI findings | Generalized cerebral and pontine atrophy |
Dilated perivascular spaces Cerebrovascular disease Cerebellar atrophy |
| Substantia nigra pathology |
Lewy bodies absent Gliomatosis |
Lewy bodies present Gliomatosis |
| Cerebellar pathology | Gliomatosis | Gliomatosis |
| Basal ganglia pathology | Gliomatosis | Gliomatosis |